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- CasNo 51871-62-6
- Purity 99%
Quality Factory Supply 99% Pure (S)-3-(Boc-amino)-4-phenylbutyric acid 51871-62-6 with Efficient Delivery
- Molecular Formula: C15H21 N O4
- Molecular Weight: 279.336
- Melting Point: 100-104 ºC
- Boiling Point: 444.8°Cat760mmHg
- PKA: 4.43±0.10(Predicted)
- Flash Point: 222.8°C
- PSA： 75.63000
- Density: 1.139
- LogP: 2.98800
51871-62-6 Relevant articles
Synthesis of enantiomerically pure δ-benzylproline derivatives
Rodríguez, Isabel,Calaza, M. Isabel,Jiménez, Ana I.,Cativiela, Carlos
, p. 3310 - 3318 (2015)
The (2S,5R) stereoisomer of 5-benzylprol...
Synthesis method of chiral N-Boc-3-amino-4-aryl-butyric acid
-
Paragraph 0032; 0033; 0034; 0035; 0036, (2017/08/28)
The invention relates to a synthesis met...
Protein-protein interface mimicry by an oxazoline piperidine-2,4-dione
Li, Xun,Taechalertpaisarn, Jaru,Xin, Dongyue,Burgess, Kevin
supporting information, p. 632 - 635 (2015/03/05)
Representative minimalist mimics 1 were ...
Antiplasmodial activity of new 4-aminoquinoline derivatives against chloroquine resistant strain
Sinha, Manish,Dola, Vasanth R.,Agarwal, Pooja,Srivastava, Kumkum,Haq, Wahajul,Puri, Sunil K.,Katti, Seturam B.
, p. 3573 - 3586 (2014/07/07)
Emergence and spread of multidrug resist...
51871-62-6 Process route
-
-
60398-41-6
(3S)-tert-butyl 1-benzyl-3-diazo-2-oxopropylcarbamate
-
-
51871-62-6
(S)-3-tert-butoxycarbonylamino-4-phenylbutanoic acid
Conditions
| Conditions | Yield |
|---|---|
|
With
silver benzoate;
In
1,4-dioxane; water;
microwave irradiation;
|
90%
|
|
With
silver benzoate; sodium carbonate;
In
1,4-dioxane; water;
at 20 ℃;
for 0.75h;
Sonication;
|
86%
|
|
With
silver benzoate;
In
1,4-dioxane; water;
at 70 ℃;
|
82%
|
|
With
water; silver(I) acetate; triethylamine;
In
tetrahydrofuran;
for 3h;
|
76%
|
|
With
silver trifluoroacetate;
In
tetrahydrofuran; water; triethylamine;
at 20 ℃;
for 3h;
|
44%
|
|
With
hydrogenchloride; sodium carbonate; sodium thiosulfate; silver(l) oxide;
Yield given. Multistep reaction;
1.) water, dioxane, 81-85 deg C, 1.5 h 2.) water, 5 deg C;
|
|
|
With
sodium carbonate; sodium thiosulfate; silver(l) oxide;
In
1,4-dioxane; water;
for 1h;
Heating;
|
|
|
With
silver benzoate;
In
1,4-dioxane; water;
at 70 ℃;
for 5h;
|
|
|
With
silver trifluoroacetate;
|
|
|
With
TEA; silver trifluoroacetate;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
|
|
|
Multi-step reaction
with
2
steps
1: 70 percent / silver benzoate; Et3
N / tetrahydrofuran / 3 h / 20 °C
2: H2
/ Pd/C / methanol / 10 h / 750.06 Torr
With
hydrogen; silver benzoate; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
|
|
|
Multi-step reaction
with
2
steps
1: 100 percent / silver benzoate; Et3
N / 18 h / 20 °C
2: 19 percent / 10 percent aq. NaOH / methanol / 18 h / 20 °C
With
sodium hydroxide; silver benzoate; triethylamine;
In
methanol;
1: Rearrangement / 2: Hydrolysis;
|
|
|
With
silver benzoate; silica gel;
In
ethyl acetate;
at 50 ℃;
for 0.5h;
|
|
|
(3S)-tert-butyl 1-benzyl-3-diazo-2-oxopropylcarbamate;
In
tetrahydrofuran;
at 20 ℃;
for 0.166667h;
Irradiation;
Flow reactor;
With
water;
Flow reactor;
|
-
![methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoate](/upload/2026/6/90aa5244cda441ed84061352e6b95937_59fd6c1f-8c53-40fe-933a-ff53be94914d.png)
-
60398-42-7,142854-48-6
methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoate
-
-
51871-62-6
(S)-3-tert-butoxycarbonylamino-4-phenylbutanoic acid
Conditions
| Conditions | Yield |
|---|---|
|
With
lithium hydroxide; water;
In
1,4-dioxane;
for 20h;
|
92%
|
|
With
sodium hydroxide;
In
methanol;
at 20 ℃;
for 18h;
|
19%
|
|
With
potassium carbonate;
In
methanol; water;
|
|
|
With
lithium hydroxide;
In
1,4-dioxane; water;
for 20h;
|
|
|
With
lithium hydroxide;
In
tetrahydrofuran; methanol; water;
|
|
|
With
water; sodium hydroxide;
In
methanol;
at 0 - 20 ℃;
for 2h;
|
51871-62-6 Upstream products
-
186581-53-3
diazomethane
-
13734-34-4
N -tert -butoxycarbonyl-L -phenylalanine
-
60398-41-6
(3S)-tert-butyl 1-benzyl-3-diazo-2-oxopropylcarbamate
-
60398-42-7
methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoate
51871-62-6 Downstream products
-
115364-92-6
(S)-N-tert-butyloxycarbonyl-3-amino-4-phenyl-N'-(benzyloxy)butanamide
-
130944-47-7
3-[(tert-butoxycarbonyl)amino]-4-phenylbutanaldehyde
-
114645-20-4
(S)-3-amino-4-phenylbutanoic acid trifluoroacetate
-
138165-77-2
(S)-3-amino-4-phenylbutanoic acid hydrochloride
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