What is the CAS number for ODM-201?

The CAS number of ODM-201 is 1297538-32-9.

What is ODM-201 (1297538-32-9) used for?

ODM-201 is an androgen receptor (AR) antagonist (Ki = 11 nM). It inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively). ODM-201 prevents androgen-induced AR nuclear translocation in AR-overexpressing HS-HEK293 and LNCaP cells and suppresses androgen-induced proliferation of VCaP cells (IC50 = 230 nM). In vivo, ODM-201 (50 mg/kg per day) reduces tumor growth in a VCaP castrated mouse xenograft model. It also inhibits tumor growth without increasing serum testosterone levels in a VCaP intact mouse xenograft model.

What is the CAS number for ODM-201?

The CAS number of ODM-201 is 1297538-32-9.

What is ODM-201 (1297538-32-9) used for?

ODM-201 is an androgen receptor (AR) antagonist (Ki = 11 nM). It inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively). ODM-201 prevents androgen-induced AR nuclear translocation in AR-overexpressing HS-HEK293 and LNCaP cells and suppresses androgen-induced proliferation of VCaP cells (IC50 = 230 nM). In vivo, ODM-201 (50 mg/kg per day) reduces tumor growth in a VCaP castrated mouse xenograft model. It also inhibits tumor growth without increasing serum testosterone levels in a VCaP intact mouse xenograft model.

Location:Home > Pharmaceutical

ODM-201

CasNo 1297538-32-9
Purity 99%

Inquery

Good factory exports good ODM-201 1297538-32-9 We supply high quality ODM-201 (CAS 1297538-32-9), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the ODM-201 ?

ODM-201 is , while it's Molecular Formula is C19H19ClN6O2. ODM-201 is a compound being used as a novel next-generation androgen receptor-directed therapy for prostate cancer.

How to get the best price on ODM-201?

Hangzhou B&P Biotech Co,.Ltd is a quality supplier and manufacturer of ODM-201 . You can buy high quality, low price ODM-201 1297538-32-9 here. Contact us.