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1.What is the Chlorosulfonyl isocyanate ?

Clear liquid, colourless

Chlorosulfonyl isocyanate (CSI) is a versatile reagent used in various synthetic applications, including the cyanation of pyrrole acetals, the synthesis of uridine 5’-diphosphate glucose analogues, and the preparation of N-hydroxysulfamides. It reacts with substrates like pyrrole acetals, though its utility can be limited by competing decomposition reactions under certain conditions. In glycosylation inhibitor synthesis, CSI facilitates the introduction of key functional groups, while in sulfamide chemistry, it serves as a precursor for N-Boc-sulfamoyl chloride, enabling the construction of biologically active N-hydroxysulfamides. Additionally, CSI participates in the formation of β-lactam intermediates for carbapenem antibiotics. Its reactivity underscores its importance in organic synthesis, particularly in constructing heterocycles and functionalized biomolecules.

2.What is the CAS number for Chlorosulfonyl isocyanate ?

The CAS number of Chlorosulfonyl isocyanate is 1189-71-5.

3.What are another words for Chlorosulfonyl isocyanate ?

Synonyms?for?Chlorosulfonyl isocyanate 1189-71-5:CSI;Chlorosulfuric acid, anhydride with isocyanic acid;Chlorosulphonyl isocyanate;Sulfuryl chlorideisocyanate;Isocyanic acid, anhydride with chlorosulfuric acid;N-Chlorosulfonyl isocyanate;N-Chlorosulphonyl isocyanate;Sulfonyl chlorideisocyanate;Isocyanicacid, anhydride with chlorosulfonic acid (6CI);

4.What is Chlorosulfonyl isocyanate (1189-71-5) used for?

Employed in a regio- and diastereoselective introduction of a protected amino group in a synthesis of chiral, polyhydroxylated piperidines. Generation of ureas from amino groups in a synthesis of benzimidazolones.

InChI:InChI=1/CClNO3S/c2-7(5,6)3-1-4

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