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5-HYDROXY-4-METHYL-2(5H)FURANONE


  • CasNo40834-42-2
  • Purity99%
Inquery

Offer Chemical Raw Material 5-HYDROXY-4-METHYL-2(5H)FURANONE 40834-42-2 In Stock

  • Molecular Formula:C5H6O3
  • Molecular Weight:114.101
  • Vapor Pressure:0mmHg at 25°C 
  • Refractive Index:1.529 
  • Boiling Point:328.121 °C at 760 mmHg 
  • PKA:10.04±0.40(Predicted) 
  • Flash Point:163.168 °C 
  • PSA:46.53000 
  • Density:1.35 g/cm3 
  • LogP:-0.19210 

5-HYDROXY-4-METHYL-2(5H)FURANONE(Cas 40834-42-2) Usage

InChI:InChI=1/C5H6O3/c1-3-2-4(6)8-5(3)7/h2,5,7H,1H3

40834-42-2 Relevant articles

Scalable Synthesis of 3-Ethyl-4-methyl-1,5-dihydro-2 H -pyrrol-2-one: An Important Building Block of the Antidiabetic Drug Glimepiride

Chavan, Subhash P.,Pawar, Ambaji A.,Patil, Niteen B.,Kadam, Appasaheb L.,Shinde, Shrikrishna S.

, p. 3480 - 3484 (2020)

A four-step, practical, and easily scala...

Synthesis of a 13C-labelled seed-germination inhibitor (3,4,5-trimethylfuran-2(5H)-one) for the mode of action elucidation

Po?ta, Martin,Soós, Vilmos,Beier, Petr

, p. 1475 - 1480 (2018)

Abstract: It has been found that the but...

THREE COMPONENT CO-CRYSTAL FORMATION BETWEEN DIASTEREOMERIC MIXTURES OF 3-ALKYL-4-((S)-1'PHENYLETHYLAMINO) BUTANOIC ACID AND OPTICALLY PURE 1, 1'-BI-2-NAPHTHOL

-

Page/Page column 21-22, (2012/02/02)

A ternary co-crystal consisting of 1 :0....

Synthesis of γ-hydroxybutenolides applying crossed aldol condensation in the presence of a bulky Lewis acid and their anti-tumor activity

Yamano, Yumiko,Fujita, Yumi,Mizuguchi, Yukari,Nakagawa, Kimie,Okano, Toshio,Ito, Masayoshi,Wada, Akimori

, p. 1365 - 1370 (2008/09/16)

An improved synthesis of γ-hydroxybuteno...

40834-42-2 Process route

propionaldehyde
123-38-6

propionaldehyde

Glyoxilic acid
298-12-4

Glyoxilic acid

5-hydroxy-4-methyl-5H-furan-2-one
40834-42-2

5-hydroxy-4-methyl-5H-furan-2-one

Conditions
Conditions Yield
With morpholine; hydrogenchloride; In water; at 20 ℃; for 13h; Reflux;
76%
With morpholine; In 1,4-dioxane; water;
Glyoxilic acid; With morpholine; In n-heptane; water; at 0 - 20 ℃;
propionaldehyde; In n-heptane; water; at 20 - 45 ℃;
With hydrogenchloride; In n-heptane; water; at 20 ℃;
citraconic acid anhydride
616-02-4

citraconic acid anhydride

5-Hydroxy-3-methyl-5H-furan-2-one
931-23-7

5-Hydroxy-3-methyl-5H-furan-2-one

5-hydroxy-4-methyl-5H-furan-2-one
40834-42-2

5-hydroxy-4-methyl-5H-furan-2-one

Conditions
Conditions Yield
With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; at -30 - -15 ℃; for 3h; Inert atmosphere;
60%
7%

40834-42-2 Upstream products

  • 616-02-4
    616-02-4

    citraconic acid anhydride

  • 123-38-6
    123-38-6

    propionaldehyde

  • 298-12-4
    298-12-4

    Glyoxilic acid

  • 563-96-2
    563-96-2

    2,2-dihydroxyacetic acid

40834-42-2 Downstream products

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    41438-10-2

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    14398-44-8

    (2Z,4E)-3-methyl-5-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)-2,4-pentadienoic acid

  • 120263-06-1
    120263-06-1

    5-(d-menthyloxy)4-methyl-2(5H)-furanone

  • 120263-07-2
    120263-07-2

    (5S)-5-<(+)-menthyloxy>-4-methyl-2(5H)furanone

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