Cianidanol


  • CasNo 154-23-4
  • Purity 99%
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What is the Cianidanol ?

Cianidanol is Tan solid, while it's Molecular Formula is C15H14O6. Cianidanol, also known as (+)-catechin; (+)-3,3′4′,5,7-flavanepentol; 3,3′,4′, 5,7-pentahydroxyflavane, [R,3S]-2-[3,4-dihydroxyphenyl]-3,4-dihydro-1[2H]- benzopyran-3,4,7-triol, or 2-(3,4-dihydroxyphenyl)-3,4-dihydro-(2r-trans)-2h- 1-benzopyran-7-triol, is a flavonoid associated with a variety of blood disorders. An association of cianidanol and immune hemolytic anemia and thrombocytopenia has been suggested in numerous case reports. In several reports, the presence of flavonoid-dependent antibodies against red blood cells is evident with cianidanol combining with erythrocyte membranes and inducing development of autoantibodies and antibodies.Several patients had platelet antibodies with increased serum-bindable IgG values without the presence of cianidanol and several with high platelet-associated IgG levels.Antibodies against cianidanol were not detectable in certain cases.The hemolytic anemia caused acute renal failure in some patients and can be life threatening, leading to fatalities. Upon cessation of treatment with cianidanol, hematology appears to return to normal over time.These side effects do not appear to be specific to cianidanol as the formation of IgE and IgG antibodies to troxerutin (Venoruton) and silymarin (Kegalon) was also evident with patients presenting with fever, skin eruptions, and intravascular hemolysis often demonstrating high IgG titers.Furthermore, cianidanol-induced hemolysis might also occur after sensitization by other flavonoids including rutin.

What is the CAS number for Cianidanol ?

The CAS number of Cianidanol is 154-23-4.

More information of Cianidanol 154-23-4 are:

Synonyms

2H-1-Benzopyran-3,5,7-triol,2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-trans)-;(+)-(2R:3S)-5,7,3',4'-Tetrahydroxyflavan-3-ol;(+)-Catechin;(+)-Cianidanol;Catechinic acid;Catergen;Cyanidanol;D-(+)-Catechin;D-Catechol;NSC 2819;Teafuran 30A;

CAS?Number

154-23-4

Molecular Formula

C15H14O6

Molecular Weight

290.273

Density

1.593 g/cm3

Melting Point

175-177 °C (anhydrous)(lit.)

Boiling Point

630.4 °C at 760 mmHg

Flash Point

335 °C

HS CODE

29329990

PSA

110.38000

LogP

1.54610

Pka

9.54±0.10(Predicted)

What is Cianidanol (154-23-4) used for?

Cianidanol, also known as (+)-catechin, is a flavonoid compound that belongs to the polyphenolic antioxidant class. It is associated with a variety of blood disorders and has been found to have both beneficial and adverse effects on human health.

InChI:InChI=1/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1

Articles related to Cianidanol:

Article

Source

The epimerase activity of anthocyanidin reductase from Vitis vinifera and its regiospecific hydride transfers

Gargouri, Mahmoud,Chaudiere, Jean,Manigand, Claude,Mauge, Chloe,Bathany, Katell,Schmitter, Jean-Marie,Gallois, Bernard

, p. 219 - 227 (2010)

Effects of epigallocatechin gallate on the stability of epicatechin in a photolytic process

Huang, Shiuh-Tsuen,Hung, Yi-An,Yang, Meei-Ju,Chen, Iou-Zen,Yuann, Jeu-Ming P.,Liang, Ji-Yuan

, (2019)

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